Tuesday, 25th October
3rd Metabolic Diseases; Breakthrough Discoveries in Diabetes & Obesity 2022
Days
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Speakers
Session 4: Neural Control of Energy Balance
8:30AM - 10:30AM
Tuesday, 25th October
Chairs: Herbert Herzog & Lori Zeltser
Basal Ganglia Adaptations Following Obesity and Weight Loss
-
Lex Kravitz
Human exome sequencing identifies rare loss-of-function variants in
GPR75
associated with leanness and protection from obesity
-
Mark Sleeman
Ontogeny of hunger
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Marcelo Dietrich
Gut-brain pathways for food intake control
-
Amber Alhadeff
Morning Tea and Networking
10:30AM - 11:00AM
Tuesday, 25th October
Session 5: Feeding and Behaviour
11:00AM - 1:00PM
Tuesday, 25th October
Chairs: Herbert Herzog & Marcelo Dietrich
Identifying systems regulating the effects of stress on eating behavior in mice
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Lori Zeltser
Conflict feeding: foraging in the face of danger
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Michael Krashes
Fat and sugar reward along the gut brain axis
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Will de Lartigue
Critical Role of Lateral Habenula Circuits in the Control of Stress-Induced Palatable Food Consumption
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Chi Kin (Kenny) Ip
Targeting cognitive inflexibility to treat anorexia nervosa – insights into the effects of psilocybin in animal models
-
Claire J Foldi
Lunch Break
1:00PM - 2:00PM
Tuesday, 25th October
Session 6: Metabolic Crosstalk
2:00PM - 4:00PM
Tuesday, 25th October
Chairs: Anton Bennett & Kendra Bence
Gut microbiota in severe obesity: importance of B vitamin status
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Karine CLEMENT
Revisiting the hierarchical organization of central and peripheral circadian clocks
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Frederic Gachon
Adipose Tissue Cellular Heterogeneneity and Interorgan Crosstalk:Impact on Diabetes and Cancer
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Philipp Scherer
Neuroimmunometabolism
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Ana Domingos
Afternoon Tea
4:00PM - 4:30PM
Tuesday, 25th October
Plenary Session 3
4:30PM - 5:30PM
Tuesday, 25th October
Chair: Tony Tiganis
Circadian Control of Systemic Metabolism in Type 2 Diabetes
-
Juleen Zierath
Poster Session 2
5:30PM - 6:30PM
Tuesday, 25th October
AgRP negative arcuate NPY neuron drive feeding under positive energy balance
-
Qi Yue
How does psilocybin improve cognitive flexibility? - Insights for anorexia nervosa
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Kyna Conn
Hypothalamic reactive astrogliosis drives metabolic disease progression through the promotion of neurofibrosis
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Rui Qi Teo
Conditional deletion of beta catenin in the mediobasal hypothalamus impairs adaptive energy expenditure in response to high fat diet and exacerbates diet-induced obesity
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Mohammed Z Rizwan
DREADD stimulation of leptin receptor expressing NPY neurons alters energy homeostasis
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Nicola Lee
Acute stress regulates Agrp neuronal activity
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Alexander Reichenbach
Temporal dynamics of AgRP neurons are critical for context-conditioned overeating in mice
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Felicia Reed
INVESTIGATING THE ROLE OF OREXIN IN A MOUSE MODEL OF FEMALE “EMOTIONAL” STRESS-INDUCED BINGE EATING
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Mia O'Shea
Why do woman overeat? Characterizing a model of ‘emotional’ stress-induced binge eating in female mice
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Robyn M Brown
Addiction-like behaviour and glutamatergic dysfunction in rat model of diet-induced obesity
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Diana Sketriene
Taste preferences and motivated behaviour towards palatable food after vertical sleeve gastrectomy in mice
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Eva Guerrero Hreins
Using a foraging task to test avoidance behaviours during conflicting hunger motivations
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Joon S Kim
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance
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Julian van Gerwen
Cross Species Analysis of Hepatic Steatosis
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Søren Madsen
Genetic Analysis of Metabolic Syndrome in Diversity Outbred mice
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Jacqueline Stoeckli
Comparing the efficacy and toxicity of small molecule mitochondrial uncouplers to identify candidates for therapeutic development
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Divya P Shah
Mitochondrial uncoupler BAM15 normalises metabolic disease in
db/db
mice
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Sing-Young Chen
Metabolic tracing of prostate cancer patient-derived xenografts identifies metabolic heterogeneity and highlights the therapeutic potential of targeting fatty acid metabolism
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Gio Fidelito
HSD17β11 is a novel regulator of lipid metabolism
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Stacey N Keenan
Proteome-wide systems genetics analysis of skeletal muscle function and metabolism
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Jeffrey Molendijk
Investigating dual inhibition of ACC and CD36 for the treatment of non-alcoholic fatty liver disease in mice
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Camille J Devereux
Microvascular pericyte characterisation in healthy and type 2 diabetic skeletal muscles
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Emily Attrill
Mouse strain-dependent variation in metabolic associated fatty liver disease (MAFLD) – A comprehensive resource tool for pre-clinical studies
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Hamzeh Karimkhanloo
Dietary amino acid restriction promotes Type 2 Diabetes remission independent of hepatic FGF21
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Andrea Y Chan
Genetic determinants of lipidomic variation and their role in cardiometabolic disease risk
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Corey Giles
Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator
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Jon S. Oakhill
Using mice to understand how the CREBRF variant drives larger size and lower diabetes risk.
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Kate L Lee
In vitro models of insulin resistance in adipose and muscle indicate differences in glucose uptake response between IGF-II and vesiculin.
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Kate L Lee
Intervention therapy targeting the inflammatory gene, RIPK1, reduces diet-induced obesity, improves insulin sensitivity and a potential marker to predict obesity risk.
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Denuja Karunakaran
Silencing PSMD9 prevents and regresses obesity and its metabolic complications
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Simon T Bond
LETMD1 is a mitochondrial inner membrane protein critical for brown fat thermogenesis
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Shihuan Kuang
A novel method for quantifying in vivo insulin action in individual mice separates insulin resistance from hyperinsulinemia
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Harry B Cutler
Effect of sex steroids on BAT thermogenic activity: Impact of menopause
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Anne Nicole De Jesus
Conference Dinner
7:00PM - 10:00PM
Tuesday, 25th October
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